Method for antogonizing inositol 1,4,5-triphosphate

Details Method for antogonizing inositol 1,4,5-triphosphate Method for antogonizing inositol 1,4,5-triphosphate

A - Human Necessities

61

K

A61K 31/795 (2006.01)

Patent

CA 2145681

Oligomers of formula (I) have been demonstrated to be effective antagonists of inositol 1,4,5-triphosphate (IP3) by com- petitively vying with IP3 for binding sites. By competitively inhibiting the activity of IP3, the oligomers of this invention can modulate the release of intracellular calcium and elicit the resultant physiological effects.

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