Method for ascertaining the history of a condition of the...

C - Chemistry – Metallurgy – 12 – Q

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150/13, 150/15

C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01)

Patent

CA 1340365

A historical time series analysis is obtained from a single sample of blood by measurement of hemoglobin and an altered hemoglobin, for example, glycohemoglobin, on a cell-by-cell basis. The results are compared by ratio of glycohemoglobin to hemoglobin on a cell-by-cell basis. Since the alteration of hemoglobin is continuous and irreversible, the ordered set of ratios represents a time-series of the cells, and any deviation from normal will be readily apparent. A time-series can also be derived for other constituents, the time-series representing historical data of the other constituents in the person from whom the blood sample was taken.

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