Method for assaying agalacto-igg and assay kits,...

Details Method for assaying agalacto-igg and assay kits,... Method for assaying agalacto-igg and assay kits,...

G - Physics

01

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G01N 33/53 (2006.01) C07K 14/42 (2006.01) C07K 14/47 (2006.01) C12N 1/21 (2006.01) C12N 15/31 (2006.01) G01N 33/564 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2268038

A method for assaying an agalacto-IgG in specimens which involves the step of reacting the specimen with a lectin adherent onto a solid phase and forming a complex of the agalacto-IgG with the lectin adherent onto the solid phase; a method for detecting rheumatism with the use of this assay method; kits for detecting the agalacto-IgG and kits for diagnosing rheumatism; and polypeptides of lectins usable in these methods and DNAs encoding the same.

On décrit un procédé de dosage d'une agalacto-IgG dans des échantillons, lequel comprend l'étape consistant à faire réagir l'échantillon avec une lectine adhérant sur une phase solide et à former un complexe de l'agalacto-IgG avec cette lectine sur phase solide. On décrit également un procédé de détection de rhumatisme à l'aide de ce procédé de dosage, des trousses de détection de l'agalacto-IgG, des trousses pour le diagnostic du rhumatisme, ainsi que des polypeptides de lectines, utilisables dans de tels procédés, et des ADN codant ces polypeptides.

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