C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/70 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2341627
The present method involves evaluating the purity of a viral gene transfer vector stock by providing an aliquot of the viral gene transfer vector stock and producing charged fragments from the aliquot. The fragments are detected by a detector that produces a sample signal corresponding to the mass-to- charge ratio of the detected fragments. This signal then is compared to a standard signal, whereby the purity of the viral gene transfer vector stock is evaluated.
La présente invention consiste à évaluer la pureté d'une population de vecteurs viraux de transfert de gènes en produisant une partie aliquote de la population de vecteurs viraux de transfert de gènes, ainsi que des fragments chargés à partir de cette partie aliquote. Les fragments sont détectés par un détecteur qui génère un signal échantillon correspondant au rapport masse/charge des fragments détectés. Ce signal est ensuite comparé à un signal standard, ce qui permet d'évaluer la pureté de la population des vecteurs viraux de transfert de gènes.
Carrion Miguel
Kovesdi Imre
Genvec Inc.
R. William Wray & Associates
LandOfFree
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