Method for asymmetric alkynylation of alpha-imino esters

C - Chemistry – Metallurgy – 07 – C

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C07C 227/32 (2006.01) C07C 229/30 (2006.01) C07C 229/32 (2006.01) C07C 229/36 (2006.01)

Patent

CA 2608845

Method for the preparation of asymmetric alkynylated -amino esters of the formula (III) wherein R1 and R2 are independently optionally substituted alkyl, cycloalkyl, aryl or heteroaryl, and Y is hydrogen or a nitrogen protecting group.

La présente invention a trait à un procédé pour la préparation d'amino-esters alkynylés de formule (III), dans laquelle R1 et R2 sont indépendamment alkyle, cycloalkyle, aryle ou hétéroaryle éventuellement substitué, et Y est hydrogène ou un groupe protecteur azote.

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