Method for bioengineering cartilage

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/08 (2006.01) A61K 35/32 (2006.01) A61L 27/00 (2006.01) A61L 27/26 (2006.01) A61L 27/38 (2006.01) A61L 27/52 (2006.01) C12N 5/00 (2006.01) C12N 5/06 (2006.01) A61K 35/12 (2006.01)

Patent

CA 2254350

A novel method for reconstructing cartilaginous tissue is provided in which isolated chondrocytes prepared into aggregates are then embedded into a hydrogel composition comprising alginate, collagen and elastin to form a chondrocyte-hydrogel construct. The construct is further cultured and prepared for transplantation in a patient to reproduce deformed or missing cartilaginous tissue which is essentially equivalent to the native tissue from which it is derived.

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