Method for breeding domesticated fowl

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) A01K 67/02 (2006.01) A01K 67/027 (2006.01)

Patent

CA 2225990

Disease resistance in domesticated fowl has been associated with the Rfp-Y system of major histocompatability genes in domesticated fowl. A method for breeding domesticated fowl to produce disease resistant offspring involves selecting at least one parent that has an Rfp-Y haplotype that is characteristic of disease resistance and mating that parent with a second parent to produce a disease resistant offspring. In a further aspect, a method for determining the Rfp-Y or B-F haplotype involves a nucleic acid amplification-single-stranded conformational polymorphism ("SSCP") method.

Chez la volaille domestique, la résistance aux maladies a été associée au système Rfp-Y des principaux gènes d'histocompatibilité. On dévoile une méthode de sélection de la volaille domestique pour produire des descendants résistants aux maladies. La méthode consiste à sélectionner au moins un parent ayant un haplotype Rfp-Y qui est caractéristique de la résistance aux maladies et à l'accoupler avec un second parent pour obtenir une descendance résistante aux maladies. Sous un aspect plus poussé, une méthode faisant appel à l'amplification des acides nucléiques-au polymorphisme des conformations simple brin (SSCP) sert à déterminer l'haplotype Rfp-Y ou B-F.

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