Method for calibrating detected mass in mass spectrometry...

G - Physics – 01 – N

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G01N 27/62 (2006.01)

Patent

CA 2621910

With respect to a mass spectrograph designed to feed a solution to interface (20) between separation analysis equipment (10) and mass spectrometer (50), any detected mass is calibrated by mixing an internal standard substance for mass calibration in the solution (sheath liquid for obtaining an electrical contact between migration buffer (16) of capillary electrophoresis unit (10) or mobile phase of liquid chromatograph or separation analysis equipment and a mass spectrometer). Consequently, without the need of spray for calibration and without the use of post-column introduction method, a mass calibration of measured substance can be simply and easily.

Dans la présente invention relative à un spectrographe de masse conçu pour envoyer une solution à une interface (20) entre un équipement d'analyse de séparation (10) et un spectromètre de masse (50), n'importe quelle masse détectée est calibrée par le mélange d'une substance standard interne pour le calibrage de masse dans la solution (liquide d'enrobage pour obtenir un contact électrique entre le tampon de migration (16) de l'unité d'électrophorèse capillaire (10) ou phase mobile de chromatographe liquide ou équipement d'analyse de séparation et spectromètre de masse). En conséquence, et sans qu'il soit besoin de pulvérisation pour le calibrage et sans utiliser de procédé d'introduction après-colonne, le calibrage de masse de la substance mesurée peut être facilité.

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