Method for carrying out the transition metal-catalyzed...

C - Chemistry – Metallurgy – 07 – C

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C07C 2/08 (2006.01) C07C 2/04 (2006.01) C07C 17/281 (2006.01)

Patent

CA 2369607

The invention relates to a method for carrying out the transition metal- catalyzed dimerization or codimerization of alkenes. The inventive method is characterized in that the dimerization or codimerization is carried out in compressed carbon dioxide which serves as a solvent. The invention also relates to methods in which the compressed carbon dioxide is used as a solvent for the dimerization or codimerization and for the successive processing of the products. The invention especially relates to the use of such methods in order to produce anti-inflammatory and pain-relieving pharmaceuticals.

L'invention concerne un procédé de dimérisation ou de codimérisation d'alcènes catalysée par un métal de transition. Ce procédé est caractérisé en ce que la dimérisation ou la codimérisation est conduite dans un dioxyde de carbone comprimé comme solvant. L'invention concerne également des procédés, selon lesquels on utilise le dioxyde de carbone comprimé comme solvant pour la dimérisation ou la codimérisation et pour le traitement ultérieur des produits. L'invention concerne notamment l'utilisation de tels procédés dans la production de produits pharmaceutiques anti-inflammatoires et analgésiques.

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