C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) G01N 27/00 (2006.01)
Patent
CA 2282725
The invention concerns a method for characterising nucleic acid duplexes comprising two sequences of nucleic acid at least partially paired, characterised in that it consists in recording at least a signature of said duplexes, which is linked to the force variation required for separating, receptively re-pairing, said two sequences, and in comparing the resulting signature with references.
La présente invention concerne un procédé de caractérisation de duplex d'acide nucléique comportant deux séquences d'acide nucléique au moins partiellement appariées, caractérisé en ce qu'on enregistre au moins une "signature" desdits duplex, qui est liée à la variation de force nécessaire pour désapparier, respectivement réapparier, lesdites deux séquences, et en ce que l'on compare la signature obtenue avec des références.
Bockelmann Ulrich
Essevaz-Roulet Baptiste
Heslot Francois
Centre National de La Recherche Scientifique - Cnrs
Ogilvy Renault
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