Method for concentrating .beta.-lactam antibiotic solution

C - Chemistry – Metallurgy – 07 – D

Patent

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260/109, 260/119

C07D 501/16 (2006.01) C07D 499/00 (2006.01) C12P 35/06 (2006.01)

Patent

CA 1177067

ABSTRACT The present invention relates to a method for concen- trating a dilute aqueous solution of a .beta.-lactam antibiotic which is readily susceptible to heat, by subjecting a dilute aqueous solution of a .beta.-lactam antibiotic, said solution containing 2 to 20% (v/v) of a lower alcohol, to concentration by means of a permeable membrane made of poly(ether/amide) or polybenzimida- zolone. The method reduces decomposition of the antibiotic during concentration.

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