C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 21/02 (2006.01) A61K 47/02 (2006.01) A61K 47/12 (2006.01) C07K 14/47 (2006.01) C07K 14/765 (2006.01) C12P 21/00 (2006.01)
Patent
CA 2506317
The present invention relates to an improved method to process, purify and/or produce biopharmaceuticals or other products involving automated blending of pH buffered solutions from water and common stocks of concentrated acids and bases and other components. This approach reduces the cost and complexity of the solution preparation systems required for producing these solutions under aseptic or sterile conditions, and reduces the material costs of the solutions themselves. This approach is particularly beneficial to use with continuously- produced feedstocks and with continuous separation operations.
La présente invention porte sur un procédé amélioré permettant de traiter, purifier et/ou produire des produits biopharmaceutiques ou autres produits et comprenant le mélange automatisé de solutions tamponnées à pH à partir d'eau et de stocks communs d'acides et de bases concentrés et d'autres composants. Ce procédé permet de réduire les coûts et la complexité des systèmes de préparation de solutions nécessaires pour produire ces solutions en conditions d'asepsie ou stériles et de réduire les coûts des matériaux des solutions elles-mêmes. Cette invention s'avère notamment bénéfique dans l'utilisation de charges produites en continu et dans des opérations continues de séparation.
Brown Peter G.
Fulton Scott P.
Smart & Biggar
Taurus Hsa Llc
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