Method for controlling a coating process

Details Method for controlling a coating process Method for controlling a coating process

G - Physics

01

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G01N 21/31 (2006.01) G01N 21/35 (2006.01) G01N 21/62 (2006.01) G01N 21/64 (2006.01) G01N 21/65 (2006.01) A61K 9/28 (2006.01)

Patent

CA 2336888

This invention relates to a method for controlling the process of manufacturing a coating of a pharmaceutical product, comprising the steps of: performing a spectrometric measurement on said coating; generating a sample vector of measurement values from said spectrometric measurement; condensing said measurement values into at least one principal parameter; comparing said at least one principal parameter to a predetermined corresponding model parameter; determining deviations of said at least one principal parameter from said corresponding model parameter and extracting information directly related to the quality of said coating; and controlling the process on basis, at least partly, of said information.

L'invention concerne un procédé permettant de commander le procédé de production d'un revêtement d'un produit pharmaceutique. Ce procédé consiste: à effectuer une mesure spectrométrique sur ce revêtement; à générer un vecteur échantillon des valeurs obtenues par cette mesure; à résumer ces valeurs de mesure en au moins un paramètre principal; à comparer ce ou ces paramètre(s) principal/principaux à un paramètre modèle correspondant prédéterminé; à déterminer les écarts de ce ou ces paramètre(s) principal/principaux par rapport à ce paramètre modèle et à extraire les informations concernant directement la qualité de ce revêtement; et à commander le processus, au moins partiellement, sur la base de cette information.

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