Method for controlling bleeding

Details Method for controlling bleeding Method for controlling bleeding

A - Human Necessities

61

K

167/103.34

A61K 35/16 (2006.01) A61K 9/127 (2006.01) A61K 9/50 (2006.01) A61K 38/48 (2006.01)

Patent

CA 1276882

ABSTRACT OF THE DISCLOSURE Factor VIII:C deficiency in a hemophilic mammal may be bypassed by infusion of a synergistic mixture of a phospholipid and Factor Xa so that the cascade process of blood clotting may continue. The proportions of phospholipid and Factor Xa in the mixture are critical as too little Xa has no effect while too much is toxic (thrombogenic). Infusion of the phosphilipid-Factor Xa mixture into normal mammals enhances the natural clotting rate and provides a method for rapidly controlling bleeding in emergency situations.

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