G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/53 (2006.01) A61K 31/00 (2006.01) A61K 31/10 (2006.01) A61P 9/00 (2006.01) G01N 33/483 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2672322
The present invention relates to methods for detecting a oxidative stress in a biological sample, methods of determining a cumulative record of oxidative injury, and methods of diagnosing diseases of aging, such as cardiovascular diseases, based on the presence or absence of a biomarker or a component thereof. The present invention also relates to a kit for detecting oxidative stress in a biological sample comprising a stabilizing reactant and an antibody.
L'invention porte sur des procédé: de détection d'un biomarqueur de stress oxydatif dans un échantillon biologique, de détermination du cumul des lésions oxydatives, et de diagnostic des maladies dues au vieillissement telles que les maladies cardio-vasculaires, se basant sur la présence ou l'absence d'un biomarqueur ou de l'un de ses fragments. L'invention porte également sur une trousse de détection du stress oxydatif dans un échantillon biologique, consistant à stabiliser un réactant et un anticorps.
Asselin Caroline
Bouchard Bertrand
Comte Blandine
Des Rosiers Christine
Tardif Jean-Claude
Centre Hospitalier Universitaire Sainte-Justine
Institut de Cardiologie de Montreal
Tessier Louis
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