G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/92 (2006.01)
Patent
CA 2333946
The invention relates to a method for detecting neuropathologies by measuring apolipoprotein D (ApoD) in a sample containing cerebrospinal fluid sample from a patient. The method comprises the steps of measuring a concentration of apolipoprotein D (ApoD) in a cerebrospinal fluid sample from the patient suspected of having a neuropathology and/or a predisposition to such a neuropathology and comparing the concentrations obtained previously with a concentration of ApoD from a non-neuropathological sample. A higher concentration of ApoD in the patient sample is indicative of a neuropathology.
La présente invention concerne un procédé permettant de détecter des neuropathologies en mesurant l'apolipoprotéine D (ApoD) dans un prélèvement de liquide céphalo-rachidien provenant d'un patient. Le procédé consiste à mesurer la concentration d'apolipoprotéine D (ApoD) dans un prélèvement de liquide céphalo-rachidien provenant d'un patient susceptible de souffrir d'une neuropathologie et/ou de présenter une prédisposition à une neuropathologie, et à comparer la concentration obtenue avec une concentration d'ApoD provenant d'un prélèvement non neuropathologique. Une concentration plus élevée d'ApoD dans le prélèvement du patient indique une neuropathologie.
Poirier Judes
Rassart Eric
Terrisse Laurence
Ogilvy Renault
Universite Du Quebec A. Montreal
University Mcgill
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