Method for detecting abnormal epithelial cell shedding

Details Method for detecting abnormal epithelial cell shedding Method for detecting abnormal epithelial cell shedding

A - Human Necessities

61

K

A61K 49/00 (2006.01)

Patent

CA 2280133

A method for detecting abnormal cell shedding rates of mature epithelial cells of a warm-blooded animal, such as the epithelial cells of the gastric or colonic glands. A labeling composition containing, e.g., a cyanine dye is applied to epithelial cells, following which the site is observed over time. Abnormal cell shedding rates are indicative of disease states such as carcinoma.

L'invention concerne une méthode de détection de taux anormaux d'élimination de cellules épithéliales mûres chez un homéotherme, telles que les cellules épithéliales des glandes gastriques ou du côlon. On applique aux cellules épithéliales une composition de marquage contenant, par exemple, une matière colorante sur base de cyanine, puis le site est placé sous observation pendant un temps déterminé. Des taux anormaux d'élimination de cellules indiquent la présence d'affections telles que des carcinomes.

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