Method for detecting an inflammatory disease or cancer

G - Physics – 01 – N

Patent

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Details

G01N 30/72 (2006.01) G01N 33/49 (2006.01) G01N 33/50 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2629797

A method of detecting an inflammatory disease or a cancer in a test subject comprising determining the amount of plasmenyl-PE or a biomarker having a mass charge ratio of approximately 698.2, 722.2, 726.2 or 750.2 in a sample of bodily fluid taken from the test subject and comparing the amount of plasmenyl- PE (or the biomarker) in the sample of the bodily fluid from the test subject to a range of amounts of plasmenyl-PE (or the biomarker) found in samples of the bodily fluid from a group of normal subjects of the same species as the test subject and lacking the inflammatory disease or the cancer, whereby a change in the amount of the plasmenyl-PE (or the biomarker) (such as a lower amount) in the sample of the bodily fluid from the test subject indicates the presence of the inflammatory disease or the cancer.

L'invention concerne une méthode de dépistage d'une maladie inflammatoire ou d'un cancer chez un sujet testé qui consiste à déterminer la quantité de plasményle-PE ou d'un biomarqueur présentant un rapport masse/charge d'environ 698,2, 722,2, 726,2 ou 750,2 dans un échantillon de liquide corporel prélevé sur le sujet testé et à comparer la quantité de plasményle-PE (ou de biomarqueur) dans l'échantillon de liquide corporel du sujet testé avec une gamme de quantités de plasményle-PE (ou du biomarqueur) trouvées dans des échantillons du liquide corporel prélevés sur un groupe de sujets normaux de la même espèce que le sujet testé et non atteints de cette maladie inflammatoire ou de ce cancer, un changement de quantité du plasményle-PE (ou du biomarqueur) (tel qu'une quantité inférieure) dans l'échantillon du liquide corporel du sujet testé indiquant la présence de la maladie inflammatoire ou du cancer.

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