Method for detecting calpain 3 activity in a biological...

Details Method for detecting calpain 3 activity in a biological... Method for detecting calpain 3 activity in a biological...

C - Chemistry, Metallurgy

12

N

C12N 9/64 (2006.01) C12N 15/57 (2006.01) C12N 15/63 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2429429

The invention concerns a peptide coupled to at least a fluorogenic or colorogenic reporter molecule, characterised in that it contains at least a sequence of amino acids capable of being cleaved by calpain 3. The invention also concerns a method for detecting in vitro calpain 3 activity in a biological sample.

Peptide couplé à au moins une molécule rapporteuse fluorogénique ou colorogénique, caractérisé en ce qu'il contient au moins une séquence d'acides aminés apte à être clivée par la calpaine 3. Méthode de détection in vitro de l'activité de la calpaine 3 dans un échantillon biologique.

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