G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/574 (2006.01) G01N 33/92 (2006.01)
Patent
CA 2284630
The present invention is methods for detecting the presence of cancer in a subject by determining the concentrations of lysophospholipids in a sample of bodily fluid taken from a test subject and comparing these concentrations to concentrations present in samples taken from normal subjects without cancer to detect altered levels of the lysophospholipids indicating the presence or absence of cancer. The methods may be used for diagnosis and prognosis of cancers such as a gynecological cancer and breast cancer in a subject and to monitor the results of therapy of over time.
L'invention porte sur procédé de détection de cancers par mesure de la concentration des lysophospholipides dans un échantillon de fluides corporels prélevés chez un sujet test et comparaison de ces concentrations avec celles d'échantillons prélevés chez des sujets normaux ne présentant pas de cancer. On peut ainsi détecter les nivaux anormaux de lysophospholipides indiquant la présence ou l'absence de cancer. Le procédé peut servir pour diagnostiquer ou pronostiquer des cancers tels que des cancers gynécologiques ou du sein et observer les résultats d'un traitement dans le temps.
Gaudette Douglas C.
Holub Bruce J.
Mills Gordon B.
Atairgin Biotecghnologies Inc.
Osler Hoskin & Harcourt Llp
University Of Guelph
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