Method for detecting cellular pathology

Details Method for detecting cellular pathology Method for detecting cellular pathology

G - Physics

01

N

150/14, 167/37

G01N 33/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 1340182

The invention provides a method for the detection of cellular pathology by means of an immunoassay to determine the presence of stable breakdown products, termed BDP's or BDP1 and BDP2, of the cytoskeleton component spectrin. In one aspect of the invention, the components from a sample of spectrin-containing cells are physically separated, as by exposure to an electric field, in such a way that BDP and spectrin are separated. Antibodies reactive with BDP are then contacted with the separated sample, and their binding to that portion of the sample containing any BDP determined.

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