Method for detecting disease markers

Details Method for detecting disease markers Method for detecting disease markers

G - Physics

01

N

G01N 27/447 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2694349

Disease specific markers, in particular cancer markers, can be detected by electrophoretically separating proteins and protein complexes from a biological sample on a protein binding polymeric membrane in a low conductivity, water-miscible organic solvent buffer. Electrophoretic separation profiles representing different diseases can be produced, and used in the diagnosis or prognosis of these diseases.

L'invention porte sur des marqueurs spécifiques de maladie, en particulier des marqueurs du cancer, qui peuvent être détectés par séparation électrophorétique de protéines et de complexes protéiques à partir d'un échantillon biologique sur une membrane polymère de liaison à la protéine dans un tampon de solvant organique miscible dans l'eau, de faible conductivité. Des profils de séparation électro-phorétique représentant différentes maladies peuvent être produits, et utilisés dans le diagnostic ou le pronostic de ces maladies.

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