Method for detecting htlv-iii neutralizing antibodies in sera

Details Method for detecting htlv-iii neutralizing antibodies in sera Method for detecting htlv-iii neutralizing antibodies in sera

G - Physics

01

N

167/139, 167/37

G01N 33/569 (2006.01) C07K 16/10 (2006.01) G01N 33/577 (2006.01)

Patent

CA 1271417

Abstract of the Disclosure The invention relates to a method of measuring natural human antibodies in sera which will neutralize HTLV-III infection in an in vitro assay. Cell-free virus is incubated with serum and used to infect H9 cells, which are then put in a culture for three days. The viral infectivity is then assayed using a monoclonal antibody specific for HTLV-III p24 in an immune fluores- cent assay.

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