Method for detecting mutated alleles

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) G01N 27/447 (2006.01) G01N 30/02 (2006.01) G01N 30/46 (2006.01)

Patent

CA 2283188

The invention relates to a method for detecting mutated allels in an excess of wild type allels. According to said method, said wild type allels are isolated by means of a separation process using a carrier which is bonded to one or several oligonucleotides, said oligonucleotides being complementary to the wild type allels.

L'invention concerne une méthode qui permet de détecter des allèles mutés dans un excédent d'allèles de types sauvage. On sépare les allèles de type sauvage par une technique de séparation, dans laquelle on utilise un support sur lequel sont fixés un ou plusieurs oligonucléotides complémentaires de l'allèle de type sauvage.

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