Method for detecting or quantifying basophils and eosinophils

Details Method for detecting or quantifying basophils and eosinophils Method for detecting or quantifying basophils and eosinophils

G - Physics

01

N

G01N 33/68 (2006.01) C07K 16/28 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2342738

The invention concerns a method for detecting or quantifying eosinophils and basophils, which consists in contacting a sample possibly containing said eosinophils or basophils with an IL-5 anti-receptor (alpha-chain) monoclonal antibody which does not interfere with IL-5 fixation to its receptor and does not inhibit the IL-5 biological activity to detect and, if required, to quantify eosinophils and basophils. The invention also concerns a kit for detecting or quantifying eosinophils or basophils and an anti-IL5R antibody.

Un procédé pour la détection ou la quantification des éosinophiles et des basophiles, comprenant la mise en contact d'un échantillon contenant éventuellement lesdits éosinophiles ou basophiles avec un anticorps monoclonal anti-récepteur de l'IL-5 (chaîne alpha) qui n'interfère pas avec la fixation de l'IL5 à son récepteur et qui n'inhibe pas l'activité biologique de l'IL-5 pour détecter et si désiré procéder à la quantification des éosinophiles et des basophiles, un kit pour la détection ou la quantification des éosinophiles et des basophiles et un anticorps anti-RIL-5.

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