C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/18 (2006.01) A61K 31/4196 (2006.01) A61K 31/454 (2006.01) A61P 31/10 (2006.01) C07D 401/12 (2006.01) C07D 521/00 (2006.01) C12Q 1/04 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2391274
A novel method for evaluating an effect of an antimicrobial agent which comprises removing the antimicrobial agent remaining in a biological sample infected with a pathogenic microorganism or the like by removing the antimicrobial agent and thereafter detecting the viable pathogenic microorganism in the biological sample or infected site to thereby accurately evaluate the effect of the antimicrobial agent on the pathogenic microorganism without being effected by the remaining antimicrobial agent. The novel method also provides a screening method for therapeutic agents effective for detecting pathogenic microorganisms, for treating fungal infections, in particular, onychomycosis.
L'invention concerne une méthode d'évaluation des effets médicamenteux d'un agent antimicrobien, qui consiste à éliminer l'agent antimicrobien restant dans un échantillon biologique, etc., afin d'évaluer précisément les effets médicamenteux de l'agent antimicrobien, sans que ce dernier soit affecté par l'agent antimicrobien restant. L'invention concerne également des remèdes à la mycose des ongles, qui peuvent être obtenus à partir de la méthode d'évaluation des effets médicamenteux susmentionnée.
Arika Tadashi
Nakamura Kosho
Tatsumi Yoshiyuki
Yokoo Mamoru
Kaken Pharmaceutical Co. Ltd.
Osler Hoskin & Harcourt Llp
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