G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/86 (2006.01) C12P 1/00 (2006.01) C12Q 1/34 (2006.01) C12Q 1/56 (2006.01)
Patent
CA 2539034
The present invention relates to a method for determining the amount of procoagulant phospholipid in a sample, said method comprising steps (i) to (iii) performed in the following order: (i) forming an admixture of the sample and a substrate plasma which has been rendered free or substantially free of procoagulant phospholipid sufficient to at least reduce the capacity of the substrate plasma to coagulate, wherein said substrate plasma has been rendered free or substantially free of procoagulant phospholipid by treatment with a phospholipase; (ii) contacting the admixture with a reagent for activating coagulation of plasma in conditions where procoagulant phospholipid is the rate limiting component of the mixture; and (iii) determining the clotting time of the admixture.
L'invention concerne un procédé pour déterminer la quantité de phospholipides procoagulants dans un échantillon, ledit procédé comprenant les étapes suivantes : (i) formation d'un mélange de l'échantillon et d'un plasma à substrat qui peut être exempt ou sensiblement exempt de phospholipides procoagulants suffisamment pour réduire la capacité du plasma de substrats à coaguler, ledit plasma à substrat étant exempt ou sensiblement exempt de phospholipides procoagulants par traitement au moyen d'une phospholipidase ; (ii) mise en contact du mélange avec un réactif permettant d'activer la coagulation du plasma dans des conditions, dans lesquelles le phospholipide procoagulant est le composant à taux limité du mélange ; et (iii) détermination du temps de coagulation du mélange.
Haematex Research Pty Limited
Smart & Biggar
LandOfFree
Method for detecting procoagulant phospholipid does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for detecting procoagulant phospholipid, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for detecting procoagulant phospholipid will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2046133