C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07H 21/04 (2006.01) C12N 15/09 (2006.01) C12N 15/10 (2006.01)
Patent
CA 2394428
A method of detecting a nucleic acid which comprises detecting a nucleic acid aptamer formed by hybridizing the target base sequence with a probe by using the binding activity to a ligand as an indication. By using as the nucleic acid aptamer a structure the binding activity of which widely varies depending on a mismatch of a single base (for example, three-way junction), SNP can be detected.
Procédé de détection d'un acide nucléique qui consiste à détecter un aptamère d'acide nucléique formé par hybridation de la séquence de bases cible avec une sonde en utilisant l'activité de liaison à un ligand en tant qu'indication. Grâce à l'utilisation, comme aptamère d'acide nucléique, d'une structure dont l'activité de liaison varie fortement en fonction du mésappariement d'une seule base (par exemple jonction à trois voies), il est possible de détecter des polymorphismes de nucléotide simple.
Karube Isao
Kato Teru
Katayanagi Institute
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
LandOfFree
Method for detecting target nucleotide sequences does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for detecting target nucleotide sequences, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for detecting target nucleotide sequences will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1800843