Method for detecting the risk of and for treatment of type 2...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) C12N 9/10 (2006.01) C12Q 1/48 (2006.01)

Patent

CA 2574014

A role of the human EXT2 gene in metabolic conditions such as T2D is disclosed. Methods and test kits for diagnosis, T2D risk prediction and prediction of clinical course of a metabolic condition using biomarkers related to the EXT2 gene are disclosed. Novel methods for 5 prevention and treatment of metabolic diseases based on EXT2 gene, polypeptides and EXT2 related pathways are also disclosed.

Cette invention concerne le rôle du gène EXT2 humain dans des états métaboliques tels que le diabète non insulino-dépendant. Cette invention concerne des procédés et des kits de test utilisant des biomarqueurs associés au gène EXT2 pour diagnostiquer un tel état métabolique, pour prévenir les risques de diabète non insulino-dépendant et pour prédire l'évolution clinique d'un tel état métabolique. Cette invention concerne également de nouveaux procédés pour prévenir et traiter des maladies métaboliques basées sur le gène EXT2, des polypeptides et des voies associées au gène EXT2.

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