Method for detecting, treating, and monitoring conditions...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/00 (2006.01) C12Q 1/56 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01) G01N 33/86 (2006.01)

Patent

CA 2385502

Methods for diagnosing, treating and monitoring conditions associated with activation of the coagulation response in patients suffering from conditions such as chronic fatigue syndrome, fibromyalgia and cardiovascular disease are disclosed. Diagnostic assays utilized in the methods include measurement of blood levels of fibrinogen, prothrombin fragment 1 + 2, thrombin/antithrombin complexes and soluble fibrin monomers. Treatment regimens include anticoagulant therapies comprising administering warfarin or heparin as needed.

La présente invention concerne des techniques de diagnostic, de traitement et de surveillance de pathologies associées à l'activation de la réaction de la coagulation chez des patients qui souffrent de pathologies telles que le syndrome de fatigue chronique, la cellulomyalgie et les maladies cardio-vasculaires. Les analyses de diagnostic utilisées dans ces techniques comprennent le dosage des niveaux de fibrine, des fragments de prothrombine 1+2, des complexes thrombine/antithrombine et des monomères de fibrine solubles. Les régimes de traitement incluent des thérapies anticoagulante qui comprennent l'administration de warfarine ou d'héparine selon les besoins.

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