Method for detecting uracil biosynthesis inhibitors and...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 231/20 (2006.01) A01N 43/56 (2006.01) C07D 231/32 (2006.01) C07D 401/12 (2006.01) C07D 409/12 (2006.01) C12Q 1/37 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2416039

This invention relates to a method for identifying compounds that specifically inhibit a metabolic target site or pathway in plants. Enzymes which are specifically affected by the method of the invention include plant pyramidine biosynthetic pathway enzymes, and particularly the enzymes involved in the conversion of orotate to uridine-5'-monophosphate (UMP). Further, the invention relates to a method for control of undesirable monocotyledonous and dicotyledenous plant species.

L'invention concerne une méthode d'identification des composés inhibant de manière spécifique un site ou une voie cible métabolique dans les plantes. Les enzymes spécifiquement affectées par ladite méthode comprennent les enzymes à voie de synthèse biologique de pyrimidine, et en particulier les enzymes associées à la conversion de l'orotate en uridine-5'-monophosphate (UMP). De plus, l'invention concerne une méthode de contrôle des espèces végétales monocotylédonées et dicotylédonées indésirables.

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