Method for detection of an analyte using acridinium esters...

Details Method for detection of an analyte using acridinium esters... Method for detection of an analyte using acridinium esters...

C - Chemistry, Metallurgy

07

D

260/282, 167/43,

C07D 219/04 (2006.01) C07F 9/64 (2006.01) C09K 11/06 (2006.01) C12Q 1/68 (2006.01) G01N 33/533 (2006.01) G01N 33/58 (2006.01)

Patent

CA 1339490

A method for the detection of an analyte in a fluid sample using liposomes encapsulating acridinium esters (lumisomes). Hydrophilic polysubstituted aryl acridinium esters are useful as chemiluminescent markers and can be encapsulated within liposome vesicles without significant leakage of the esters from the vesicles. The lumisomes can be coupled to molecules with biological activity, such as antigens, antibodies, and nucleic acids, and used in luminescent assays.

607098

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