Method for detection of antibody to hepatitis c virus second...

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G01N 33/576 (2006.01) C07K 14/18 (2006.01)

Patent

CA 2223277

A method for detecting antibody to HCV in a test sample. The method includes utilizing a recombinant protein that is the expression product of mammalian cells transformed by a heterologous expression vector comprising a DNA sequence encoding an E2 truncated protein. Test kits which include this recombinant protein also are provided.

Procédé de détection d'un anticorps contre le virus de l'hépatite C dansun échantillon de test. Le procédé consiste en particulier à utiliser une protéine de recombinaison qui est le produit d'expression de cellules mammifères transformées par un vecteur d'expression hétérologue comprenant une séquence d'ADN codant une protéinetronquée E2. On décrit également des matériels de test contenant cette protéine de recombinaison.

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