Method for detection of biological factors in epidermis

Details Method for detection of biological factors in epidermis Method for detection of biological factors in epidermis

A - Human Necessities

61

K

A61K 35/36 (2006.01) A61K 48/00 (2006.01) A61K 49/00 (2006.01) C12N 15/09 (2006.01) C12N 15/10 (2006.01) C12N 15/11 (2006.01) C12N 15/12 (2006.01) C12N 15/19 (2006.01) C12N 15/24 (2006.01) C12P 19/30 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2340673

Disclosed is a method for removing polynucleotide from the skin. This polynucleotide can be used to detect dermatitis and distinguish an irritant reaction from an allergic reaction by charaterizing the polynucleotide according to the polypeptide which it encodes. Additionally, provided are methods for non-invasive isolation of samples from the skin as well as kits for use in the methods provided herein.

L'invention concerne une méthode permettant le prélèvement d'un polynucléotide dans la peau. Ce polynucléotide peut servir à détecter une dermatite et à distinguer une réaction d'irritation d'une réaction allergique. A cette fin on caractérise le polynucléotide en fonction du polypeptide qu'il code. L'invention concerne en outre des procédés permettant d'isoler de façon non invasive des échantillons prélevés dans la peau, ainsi que des assortiments de matériel destinés à la mise en oeuvre de ce procédé.

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