Method for detection of human papillomavirus (hpv) for...

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G01N 33/569 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2040849

ABSTRACT Method for detection of infection with papillomavirus (PV) for diagnostic purposes, spe- cifically for diagnosing PV-associated neoplasia, on a body fluid or tissue, c h a r a c t e r i z e d in that the detection is effected by ascertaining the presence in the body fluid or tissue of IgA antibodies to the L2-encoded approximately 64 kDa papillomavirus protein, the L1-encoded approximately 54 kDa papillomavirus protein, as well as any type of antibody to an approximately 28 kDa papilloma- virus virion protein, to an approximately 14 kDa papillomavirus virion protein, or to a peptide having an amino acid sequence represented by a formula selected from the group consisting of Image Image or to such modifications of any of the peptides of said group which are substantially immunoreactive with antibodies to the original peptide.

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