Method for detection of peritoneal inflammation or infection

Details Method for detection of peritoneal inflammation or infection Method for detection of peritoneal inflammation or infection

C - Chemistry, Metallurgy

12

Q

150/15, 150/3.2

C12Q 1/34 (2006.01) C12Q 1/04 (2006.01) G01N 33/50 (2006.01)

Patent

CA 1243254

METHOD FOR DETECTION OF PERITONEAL INFLAMMATION OR INFECTION James L. Babb Timothy G. Bloomster Jon A. Rudbach Abstract Peritoneal inflammation or infection can be detected in a patient by assaying a peritoneal lavage sample from the patient for lysosomal enzymes. This is done by combining the lavage sample with a leukocyte lysing agent and a chromogenic or fluorogenic enzyme substrate specific for lysosomal enzymes. The lysosomal enzymes can then be measured, and the inflammation or infection detected, by measuring the color or fluorescence developed in the sample by action of the enzymes on the substrate.

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