Method for determining gene knockout strategies

Details Method for determining gene knockout strategies Method for determining gene knockout strategies

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12N 15/00 (2006.01) C12P 1/00 (2006.01) C40B 30/02 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2491753

A method for determining candidates for gene deletions and additions using a model of a metabolic network associated with an organism, the model includes a plurality of metabolic reactions defining metabolite relationships, the method includes selecting a bioengineering objective for the organism, selecting at least one cellular objective, forming an optimization problem that couples the at least one cellular objective with the bioengineering objective, and solving the optimization problem to yield at least one candidate.

L'invention concerne un proc~d~ permettant de d~terminer des candidats aux d~l~tions et additions g~niques au moyen d'un mod­le de r~seau m~tabolique associ~ ~ un organisme. Ledit mod­le comporte plusieurs r~actions m~taboliques d~finissant des relations de m~tabolites. Le proc~d~ consiste ~ s~lectionner un objectif de bio-ing~nierie pour ledit organisme, ~ s~lectionner au moins un objectif cellulaire, ~ former un probl­me d'optimisation qui relie les objectifs cellulaires et de bio-ing~nierie, et ~ r~soudre le probl­me d'optimisation pour obtenir au moins un candidat.

Affiliated with

Also associated with

Rating

Method for determining gene knockout strategies does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for determining gene knockout strategies, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for determining gene knockout strategies will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1733830