Method for determining genotoxicity

Details Method for determining genotoxicity Method for determining genotoxicity

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2587548

Methods for determining the genotoxicity of a test compound are provided. The method involves contacting a viable test cell with the test compound and determining the change in expression level of the indicator gene 483327G06 Rik (RIKEN cDNA). An increase in expression of at least 1.5-fold indicates that the test compound exhibits genotoxity.

Cette invention concerne des méthodes et des réactifs permettant de déterminer la génotoxicité d'un composé en fonction des réponses génomiques à des contact avec ledit composé.

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