G - Physics – 01 – N
Patent
G - Physics
01
N
167/44
G01N 33/53 (2006.01) G01N 33/68 (2006.01)
Patent
CA 1267084
A B S T R A C T A method of detecting or determining the sequence of monomers which is a topographical equivalent of the ligand which is complementary to a particular receptor of interest, the method comprises the steps of:- 1. synthesizing a plurality of catamers, each said catamer being of the general formula: D2-D1 wherein D1 represents a designated monomer selected from a first set of monomers, and D2 represents a designated monomer selected from a second set of monomers which may be the same as or different to said first set of monomers; said plurality of catamers comprising catamers in which each designated monomer is systematically varied to contain members from the respective set of monomers; 2. contacting each catamer with the receptor of interest, and, 3. detecting or determining the presence or absence of binding between each catamer and said receptor. The method may also include the synthesis of further pluralities of catamers, including catamers containing spacer molecules, to build up a sequence of monomers which is the mimotope of the ligand.
507185
Coselco Mimotopes Pty. Ltd.
Fetherstonhaugh & Co.
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