Method for determining sugar chain structure

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/34 (2006.01) C07H 3/06 (2006.01) C07H 5/06 (2006.01) C07H 13/04 (2006.01) C07H 15/26 (2006.01) C08B 37/00 (2006.01) G01N 33/50 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2130028

A method for determining the structure of an N- acetyllactosamine type of sugar chain characterized by determining the site of linkage and the mode of linkage of sugar residues at the non-reducing terminal side of a .beta.-N-acetylglucosamine residue linked to an a-mannose residue in M3 core by means of detecting the presence of the .beta.-N-acetylglucosamine residue after enzymatic or chemical treatment of said sugar chain.

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