G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/50 (2006.01)
Patent
CA 2761807
This document is related to a method for determining the cardio generative potential of mammalian cells which comprises the assessment of a CARdiac generation Potential Index (CARPI) as a function of the quantification of the expression of genes of said cells. It also relates to a method for quantitatively assessing the modification of this cardio-generative potential and the cardiogenic potential of a treatment aiming at cellular differentiation.
Cette invention concerne un procédé permettant de déterminer le potentiel cardio-générateur de cellules de mammifères, ledit procédé comprenant l'évaluation d'un indice de potentiel de génération CARdiaque (CARPI) qui est une fonction de la quantification de l'expression des gènes desdites cellules. Elle concerne également un procédé permettant d'évaluer quantitativement la modification de ce potentiel cardio-générateur et le potentiel cardiogène d'un traitement visant à différencier les cellules.
Behfar Atta
Gaussin Vinciane
Gordon-Beresford Roland
Homsy Christian
Terzic Andre
Borden Ladner Gervais Llp
Cardio3 Biosciences Sa
Mayo Foundation For Medical Education And Research
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