Method for diagnosing alzheimer disease

Details Method for diagnosing alzheimer disease Method for diagnosing alzheimer disease

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A01K 67/027 (2006.01) C12N 15/10 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2295865

The invention concerns a method for diagnosing Alzheimer disease, consisting in demonstrating one or several mutations in the genomic DNA region regulating the expression of the apolipoprotein E gene, inducing a modification of the apolipoprotein E gene, with respect to a control population or a modification of the expression relative to the alleles of the apolipoprotein E gene.

Cette invention concerne un procédé de diagnostic de la maladie d'Alzheimer, comprenant la mise en évidence d'une ou plusieurs mutations dans la région d'ADN génomique de régulation de l'expression du gène de l'apolipoprotéine E, induisant une modification de l'expression du gène de l'apolipoprotéine E, par rapport à une population témoin ou une modification de l'expression relative des allèles du gène de l'apolipoprotéine E.

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