A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) A61K 48/00 (2006.01) A61P 19/08 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2589098
The present invention relates to the field of molecular biology and medicine. The present invention relates to the use of polynucleotides encoding a mammalian PLEKHM1 polypeptide and the polypeptides encoded by these polynucleotides for regulating bone homeostasis and for diagnostic and/or therapeutic applications. The present invention further relates to vectors, host cells, antibodies, diagnostic and therapeutic methods for detecting and treating diseases, in particular bone-related diseases.
L'invention concerne le domaine de la biologie et de la médecine moléculaire. L'invention concerne l'utilisation de polynucléotides codant un polypeptide PLEKHM1 de mammifère, et les polypeptides codés par ces polynucléotides pour réguler l'homéostase osseuse et pour des applications diagnostiques et/ou thérapeutiques. L'invention concerne également des vecteurs, des cellules hôtes, des anticorps, des méthodes diagnostiques et thérapeutiques pour détecter et pour traiter des maladies, en particulier des maladies associées aux os.
Odgren Paul R.
Van Hul Wim Camiel Augusta
Van Wesenbeeck Liesbeth Louisa Hugo
Aic
Smart & Biggar
Universiteit Antwerpen (university Of Antwerp)
University Of Massachusetts
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