Method for diagnosing hepatic diseases

G - Physics – 01 – N

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G01N 33/574 (2006.01) G01N 33/576 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2590982

The invention concerns a method for early diagnosis of hepatic diseases, which consists in determining in the samples of the diseased subjects, the presence of a alipoprotein AI (Apo-AI) isoform, having oxidized W50, W108 and M112 residues. The inventive method is useful for diagnosing hepatocellular carcinoma and hepatitis B.

L'invention concerne une méthode diagnostique précoce pour maladies hépatiques, qui consiste à déterminer dans des échantillons de malades atteints, la présence d'une isoforme d'apolipoprotéine AI (Apo-AI), qui présente les résidus W50, W108 et M112 oxydés. La méthode de l'invention s'avère utile pour le diagnostic du carcinome hépatocellulaire et de l'hépatite B.

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