Method for diagnosing neurodegenerative diseases

Details Method for diagnosing neurodegenerative diseases Method for diagnosing neurodegenerative diseases

G - Physics

01

N

G01N 33/577 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2070812

2070812 9109311 PCTABS00005 Provided is a method for diagnosing in a living person an ubiquitin-associated neurodegenerative disease, such as Alzheimer's Disease, Pick's Disease, Parkinson's Disease or progressive supranuclear palsy. The method comprises assaying an aliquot of cerebral spinal fluid from the person for ubiquitin-immunoreactive substances. The invention rests on the surprising discovery that, in living persons with such diseases, but not in living persons without such diseases, there is a significant amount of ubiquitin-immunoreactive substances in the cerebrospinal fluid.

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