G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/92 (2006.01)
Patent
CA 2627082
The invention relates to a method for diagnosticating hepatic diseases consisting in measuring an apolipoprotein A4 expression in hepatic cells or tissues and in the circulation (blood, plasma, serum. A method for screening molecules for treating said diseases by bringing into contact said compounds with a mammal and for measuring the apolipoprotein A4 expression in said hepatic origin cells or in the circulation of said mammal is also disclosed.
La présente demande a pour objet une méthode de diagnostic de maladies hépatiques comprenant la mesure de l'expression de l'apolipoprotéine A4 dans les cellules ou tissus hépatiques et dans la circulation (sang, plasma, sérum). Elle est en outre relative à un procédé de criblage de molécules pour le traitement de ces maladies mise en contact desdits composés avec un mammifère et mesure de l'expression de l'apolipoprotéine A4 dans lesdites cellules d'origine hépatique ou dans la circulation dudit mammifère.
Buisson Isabelle
Casellas Pierre
Galiegue Sylvaine
Marchand Jean
Simon Dominique
Robic
Sanofi-Aventis
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