Method for differentiating mesenchymal stem cell into neural...

Details Method for differentiating mesenchymal stem cell into neural... Method for differentiating mesenchymal stem cell into neural...

C - Chemistry, Metallurgy

12

N

C12N 5/079 (2010.01) C12N 5/0775 (2010.01)

Patent

CA 2543118

The present invention provides a method of differentiating and proliferating a mesenchymal stem cell into the neural cell by culturing in a medium comprising an epidermal growth factor and a hepatocyte growth factor after confluent culture of the mesenchymal stem cell. The present invention provides more effective method of differentiating and proliferating the mesenchymal stem cell or the mononuclear cell comprising the mesenchymal stem cell into the neural cell with a neuron and an astrocyte in terms of time, efficiency and maturity as compared with conventional methods.

L'invention se rapporte à un procédé permettant de différentier et de proliférer une cellule souche mésenchymateuse dans la cellule nerveuse par la culture d'un milieu comprenant un facteur de croissance épidermique et un facteur de croissance hépatocyte après la culture confluente de la cellule souche mésenchymateuse. L'invention concerne aussi un procédé plus efficace de différentiation et de prolifération de la cellule souche mésenchymateuses ou de la cellule mononucléaire comprenant la cellule souche mésenchymateuse dans la cellule nerveuse avec une neurone et un astrocyte, en termes de durée, d'efficacité et de maturité, en comparaison avec les procédés habituels.

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