Method for differentiating mesenchymal stem cells into...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/079 (2010.01) C12N 5/0775 (2010.01) A61K 35/30 (2006.01) A61P 25/00 (2006.01) A61K 35/12 (2006.01)

Patent

CA 2444724

A method for differentiating mesenchymal stem cells of bone marrow into neural cells comprises culturing the mesenchymal stem cells in a medium containing epidermal growth factor(EGF), basic fibroblast growth factor(bFGF) and hepatocyte growth factor(HGF), and the neural cells produced thereby can be employed for the treatment of a neural disease.

La présente invention concerne un procédé pour différencier des cellules souches mésenchymateuses de moelle osseuse dans des cellules nerveuses. Ce procédé consiste à mettre en culture les cellules souches mésenchymateuses dans un milieu contenant du facteur de croissance épidermique (EGF), du facteur de croissance fibroblastique basique (FGF) et du facteur de croissance des hépatocytes (HGF). La présente invention concerne également les cellules nerveuses ainsi produites, qui peuvent être utilisées dans le traitement de maladies nerveuses.

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