C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/28 (2006.01) G01N 33/72 (2006.01) A61B 10/00 (2006.01)
Patent
CA 2158432
The presence of fecal occult blood in a stool sample is detected by mixing a liquid stool sample with an acidic liquid, such as a phosphate/citrate buffer, to precipitate hematin from the solution. The precipitated hematin is separated and the presence of absence of hemoglobin is determined by exposing the solution to a peroxidase diagnostic assay. A positive response indicates the presence of blood originating in the lower gastrointestinal tract, a leading indicator of lower GI cancer.
Fiedler Paul N.
Levine Robert A.
Wardlaw Stephen C.
Borden Ladner Gervais Llp
Fiedler Paul N.
Levine Robert A.
Wardlaw Stephen C.
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