Method for diminishing specific immune reactions

Details Method for diminishing specific immune reactions Method for diminishing specific immune reactions

C - Chemistry, Metallurgy

12

N

C12N 5/10 (2006.01) A61K 35/14 (2006.01) A61K 48/00 (2006.01) A61K 35/12 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2373016

The invention relates to an antigen-presenting cell which mainly presents predetermined antigens (monoantigenic antigen-presenting cell) and which is characterized in that the monoantigenic antigen-presenting cell is capable of dividing and one of the functions of co-stimulator receptors such as a B7 and/or CD40 receptor is suppressed.

L'invention concerne une cellule présentant un antigène, qui comporte des antigènes déterminés essentiellement antérieurement (cellule monoantigène présentant un antigène) et se caractérise en ce que dans la cellule monoantigène présentant un antigène peut se diviser et en ce qu'une des fonctions de récepteurs co-stimulateurs, tels qu'un récepteur B7 et/ou CD40 est supprimée.

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